The Hollywood couple has been dogged by rumours of a split and now the Batman Begins actress' attorney, Jonathan Wolfe, has confirmed the tragic news, just four days before Cruise turns 50 on Tuesday (3 July 2012).
In a statement released on Friday, Wolfe said, "This is a personal and private matter for Katie and her family. Katie's primary concern remains, as it always has been, her daughter's best interest."
The Mission: Impossible star exchanged vows with Holmes in a fairytale wedding in an Italian castle in 2006 and they have a six-year-old daughter, Suri.
Cruise has been divorced twice before; his first marriage to Mimi Rogers ended after less than three years together, while he split from Nicole Kidman in 2001 after 10 years. The divorce news won't be a surprise to Ahlan! readers, after we reported on the growing divide between the pair and the fact that Holmes skipped her husband's film premiere for Rock of Ages in Los Angeles earlier this month following his erotic photoshoot with two blondes. The movie superstar told red-carpet reporters his wife had business to attend to in China and couldn't change her schedule.
Meanwhile, as Cruise prepares to celebrate his 50th birthday in Iceland with his adopted son Connor, Holmes and Suri have been spotted out and about in New York City.